At times I get DNS weirdness (can’t get to google.com sites, domains go to the wrong place, etc). I think our ISP’s DNS servers are slow and get hacked a lot. One of our customers recently had a lot of issues accessing Google Apps as well, so I helped them switch their computers to use Google’s DNS servers. They were amazed by how much better everything works, and they said Google Apps/Gmail flies now.
I just switched my PC over to Google DNS and truly it’s amazing how much faster sites load, especially google.com sites (gmail, google docs, calendar, etc).